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Article

Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway.

Human molecular genetics - 1 Dec 2009

Hazra Aditi, Kraft Peter, Lazarus Ross, Chen Constance, Chanock Stephen J, Jacques Paul, Selhub Jacob, Hunter David J

Abstract excerpt

Low plasma B-vitamin levels and elevated homocysteine have been associated with cancer, cardiovascular disease and neurodegenerative disorders. Common variants in FUT2 on chromosome 19q13 were associated with plasma vitamin B12 levels among women in a genome-wide association study in the Nurses' Health Study (NHS) NCI-Cancer Genetic Markers of Susceptibility (CGEMS) project. To identify additional loci associated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 19744961
DOI: 10.1093/hmg/ddp428
PMCID: PMC2773275

Genes

FUT2
NHS
MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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