Article
The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype.
Genes & development - 1 May 1990
Kimmel B E, Heberlein U, Rubin G M
Abstract excerpt
The Drosophila homeo box gene rough is required in photoreceptor cells R2 and R5 for normal eye development. We show here that rough protein expression is limited to a subset of cells in the developing retina where it is transiently expressed for 30-60 hr. The rough protein is first expressed broadly in the morphogenetic furrow but is rapidly restricted to the R2, R3, R4, and R5 precursor cells. Ubiquitous...
Topics
- Animals
- Base Sequence
- Cell Cycle Proteins
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Eye
- Gene Expression
- Genes, Homeobox
- Heat-Shock Proteins
- Hot Temperature