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Article

senseless repression of rough is required for R8 photoreceptor differentiation in the developing Drosophila eye.

Neuron - 8 Nov 2001

Frankfort B J, Nolo R, Zhang Z, Bellen H, Mardon G

Abstract excerpt

An outstanding model to study how neurons differentiate from among a field of equipotent undifferentiated cells is the process of R8 photoreceptor differentiation during Drosophila eye development. We show that in senseless mutant tissue, R8 differentiation fails and the presumptive R8 cell adopts the R2/R5 fate. We identify senseless repression of rough in R8 as an essential mechanism of R8 cell fate...

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Identifiers

PMID: 11709152
DOI: 10.1016/s0896-6273(01)00480-9
PMCID: PMC3122332

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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