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Article

Cell-fate determination in the developing Drosophila eye: role of the rough gene.

Development (Cambridge, England) - 1 Jul 1991

Heberlein U, Mlodzik M, Rubin G M

Abstract excerpt

The homeobox-gene rough is required in photoreceptor cells R2 and R5 for normal ommatidial assembly in the developing Drosophila eye. We have used several cell-type-specific markers and double mutant combinations to analyze cell-fate determination in rough. We show that the cells that would normally become R2 and/or R5 express a marker, a lacZ insertion in the seven-up (svp) gene, which is indicative of the...

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Identifiers

PMID: 1682125
DOI: 10.1242/dev.112.3.703

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Cell-fate determination in the developing Drosophila eye: role of the rough gene.PMID 1682125Read ↗

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Two-step selection of a single R8 photoreceptor: a bistable loop between senseless and rough locks in R8 fate.Semantic proximity Read ↗

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