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Article

Cell-fate determination in the developing Drosophila eye: role of the rough gene.

Development (Cambridge, England) - 1 Jul 1991

Heberlein U, Mlodzik M, Rubin G M

Abstract excerpt

The homeobox-gene rough is required in photoreceptor cells R2 and R5 for normal ommatidial assembly in the developing Drosophila eye. We have used several cell-type-specific markers and double mutant combinations to analyze cell-fate determination in rough. We show that the cells that would normally become R2 and/or R5 express a marker, a lacZ insertion in the seven-up (svp) gene, which is indicative of the...

Topics

Animals
Cell Differentiation
Drosophila
Eye
Genes, Homeobox
Genetic Markers
Lac Operon
Microscopy, Electron
Microscopy, Electron, Scanning
Phenotype
Photoreceptor Cells
Retina

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1682125
DOI: 10.1242/dev.112.3.703

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1682125-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Cell-fate determination in the developing Drosophila eye: role of the rough gene.PMID 1682125Read ↗

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