Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Star is required in a subset of photoreceptor cells in the developing Drosophila retina and displays dosage sensitive interactions with rough.

Developmental biology - 1 Apr 1991

Heberlein U, Rubin G M

Abstract excerpt

We report that mutations at the Star locus act as dominant enhancers of the eye phenotype displayed by flies carrying a null allele of rough. Our analysis of double mutants at different stages of eye development suggests that this phenotype results from defects in the early stages of photoreceptor cell differentiation in the eye imaginal disc. Complete loss of Star function during retinal development, analyzed in...

Topics

Alleles
Animals
Drosophila melanogaster
Eye
Genes, Homeobox
Genes, Lethal
Genes, Recessive
Homozygote
Mutation
Phenotype
Photoreceptor Cells
Retina

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1672657
DOI: 10.1016/0012-1606(91)90427-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1672657-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Star is required in a subset of photoreceptor cells in the developing Drosophila retina and displays dosage sensitive interactions with rough.PMID 1672657Read ↗

Star is required for neuronal differentiation in the Drosophila retina and displays dosage-sensitive interactions with Ras1.Semantic proximity Read ↗

Characterization of Star and its interactions with sevenless and EGF receptor during photoreceptor cell development in Drosophila.Semantic proximity Read ↗

The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype.Semantic proximity Read ↗

Cell-fate determination in the developing Drosophila eye: role of the rough gene.Semantic proximity Read ↗

Reprogramming cell fate in the developing Drosophila retina: transformation of R7 cells by ectopic expression of rough.Semantic proximity Read ↗

The Drosophila roughened mutation: activation of a rap homolog disrupts eye development and interferes with cell determination.Semantic proximity Read ↗

distal antenna and distal antenna-related function in the retinal determination network during eye development in Drosophila.Semantic proximity Read ↗

senseless repression of rough is required for R8 photoreceptor differentiation in the developing Drosophila eye.Semantic proximity Read ↗

Unraveling the genetic complexity of Drosophila stardust during photoreceptor morphogenesis and prevention of light-induced degeneration.Semantic proximity Read ↗

Lobe and Serrate are required for cell survival during early eye development in Drosophila.Semantic proximity Read ↗

Requirement of the roughest gene for differentiation and time of death of interommatidial cells during pupal stages of Drosophila compound eye development.Semantic proximity Read ↗

Characterization of rho GTPase family homologues in Drosophila melanogaster: overexpressing Rho1 in retinal cells causes a late developmental defect.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.