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Article

Ectopic expression of seven-up causes cell fate changes during ommatidial assembly.

Development (Cambridge, England) - 1 Aug 1993

Hiromi Y, Mlodzik M, West S R, Rubin G M, Goodman C S

Abstract excerpt

During Drosophila ommatidial development, a single cell is selected within the ommatidial cluster to become the R7 photoreceptor neuron. The seven-up gene has been shown to play a role in this process by preventing four other photoreceptor precursors, R3/R4/R1/R6, from adopting the R7 cell fate. The seven-up gene encodes a steroid receptor-like molecule that is expressed only in those four cells that require...

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Identifiers

PMID: 8269843
DOI: 10.1242/dev.118.4.1123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Ectopic expression of seven-up causes cell fate changes during ommatidial assembly.PMID 8269843Read ↗

The Drosophila seven-up gene, a member of the steroid receptor gene superfamily, controls photoreceptor cell fates.Semantic proximity Read ↗

The Drosophila orphan nuclear receptor seven-up requires the Ras pathway for its function in photoreceptor determination.Semantic proximity Read ↗

Mechanisms of positional signalling in the developing eye of Drosophila studied by ectopic expression of sevenless and rough.Semantic proximity Read ↗

pokkuri, a Drosophila gene encoding an E-26-specific (Ets) domain protein, prevents overproduction of the R7 photoreceptor.Semantic proximity Read ↗

seven-up Controls switching of transcription factors that specify temporal identities of Drosophila neuroblasts.Semantic proximity Read ↗

Reprogramming cell fate in the developing Drosophila retina: transformation of R7 cells by ectopic expression of rough.Semantic proximity Read ↗

Cell-fate determination in the developing Drosophila eye: role of the rough gene.Semantic proximity Read ↗

Patterning of the R7 and R8 photoreceptor cells of Drosophila: evidence for induced and default cell-fate specification.Semantic proximity Read ↗

Loss of seven-up from Drosophila R1/R6 photoreceptors reveals a stochastic fate choice that is normally biased by Notch.Semantic proximity Read ↗

The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype.Semantic proximity Read ↗

seven in absentia, a gene required for specification of R7 cell fate in the Drosophila eye.Semantic proximity Read ↗

mip causes hyperinnervation of a retinotopic map in Drosophila by excessive recruitment of R7 photoreceptor cells.Semantic proximity Read ↗

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