Article
Two-step selection of a single R8 photoreceptor: a bistable loop between senseless and rough locks in R8 fate.
Development (Cambridge, England) - 1 Dec 2008
Pepple Kathryn L, Atkins Mardelle, Venken Koen, Wellnitz Kari, Harding Mark, Frankfort Benjamin, Mardon Graeme
Abstract excerpt
Patterning of sensory organs requires precise regulation of neural induction and repression. The neurocrystalline pattern of the adult Drosophila compound eye is generated by ordered selection of single founder photoreceptors (R8s) for each unit eye or ommatidium. R8 selection requires mechanisms that restrict R8 potential to a single cell from within a group of cells expressing the proneural gene atonal (ato)....
Topics
- Animals
- Animals, Genetically Modified
- Base Sequence
- Body Patterning
- Cell Cycle Proteins
- DNA Probes
- Drosophila
- Drosophila Proteins
- Enhancer Elements, Genetic
- Gene Expression Regulation, Developmental
- Genes, Insect
- Microtubule-Associated Proteins