Article
Requirement of the roughest gene for differentiation and time of death of interommatidial cells during pupal stages of Drosophila compound eye development.
Mechanisms of development - 1 May 2003
Araujo Helena, Machado Luciana C H, Octacílio-Silva Shirlei, Mizutani C Mieko, Silva Marcelo J F, Ramos Ricardo G P
Abstract excerpt
The roughest locus of Drosophila melanogaster encodes a transmembrane protein of the immunoglobulin superfamily required for several developmental processes, including axonal pathfinding in the developing optic lobe, mechanosensory bristle differentiation and myogenesis. In the compound eye, rst was previously shown to be required for establishing the correct number and spacing of secondary and tertiary pigment...
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