Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide association reveals three SNPs associated with sporadic amyotrophic lateral sclerosis through a two-locus analysis.

BMC medical genetics - 9 Sept 2009

Sha Qiuying, Zhang Zhaogong, Schymick Jennifer C, Traynor Bryan J, Zhang Shuanglin

Abstract excerpt

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal, degenerative neuromuscular disease characterized by a progressive loss of voluntary motor activity. About 95% of ALS patients are in "sporadic form"-meaning their disease is not associated with a family history of the disease. To date, the genetic factors of the sporadic form of ALS are poorly understood. METHODS: We proposed a two-stage approach based...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amyotrophic Lateral Sclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Genome-Wide Association Study

Share to Likelihood Functions

Share to Models, Genetic

Share to Odds Ratio

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 19740415
DOI: 10.1186/1471-2350-10-86
PMCID: PMC2752455

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide association reveals three SNPs associated with sporadic amyotrophic lateral sclerosis through a two-locus analysis.PMID 19740415Read ↗

Identification of interacting genes in genome-wide association studies using a model-based two-stage approach.Semantic proximity Read ↗

A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosisSemantic proximity Read ↗

Genome-wide analysis of the heritability of amyotrophic lateral sclerosis.Semantic proximity Read ↗

Causal Inference of Genetic Variants and Genes in Amyotrophic Lateral SclerosisSemantic proximity Read ↗

Second-generation Irish genome-wide association study for amyotrophic lateral sclerosis.Semantic proximity Read ↗

Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data.Semantic proximity Read ↗

A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis.Semantic proximity Read ↗

Characterising the Genetic Landscape of Amyotrophic Lateral Sclerosis: A Catalogue and Assessment of Over 1,000 Published Genetic VariantsSemantic proximity Read ↗

Amyotrophic lateral sclerosis as a complex genetic disease.Semantic proximity Read ↗

Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations.Semantic proximity Read ↗

Genetics of sporadic amyotrophic lateral sclerosisSemantic proximity Read ↗

Partitioning the genetic architecture of amyotrophic lateral sclerosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.