Article
Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data.
The Lancet. Neurology - 1 Apr 2007
Schymick Jennifer C, Scholz Sonja W, Fung Hon-Chung, Britton Angela, Arepalli Sampath, Gibbs J Raphael, Lombardo Federica, Matarin Mar, Kasperaviciute Dalia, Hernandez Dena G, Crews Cynthia, Bruijn Lucie, Rothstein Jeffrey, Mora Gabriele, Restagno Gabriella, Chiò Adriano, Singleton Andrew, Hardy John, Traynor Bryan J
Abstract excerpt
BACKGROUND: The cause of sporadic ALS is currently unknown. Despite evidence for a role for genetics, no common genetic variants have been unequivocally linked to sporadic ALS. We sought to identify genetic variants associated with an increased or decreased risk for developing ALS in a cohort of American sporadic cases. METHODS: We undertook a genome-wide association study using publicly available samples from...
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