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Article

Second-generation Irish genome-wide association study for amyotrophic lateral sclerosis.

Neurobiology of aging - 1 Feb 2015

McLaughlin Russell L, Kenna Kevin P, Vajda Alice, Bede Peter, Elamin Marwa, Cronin Simon, Donaghy Colette G, Bradley Daniel G, Hardiman Orla

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a heritable neurological disease for which the underlying genetic etiology is only partially understood. In Ireland, 83%-90% of cases are currently unexplained. Through large international collaborations, genome-wide association studies (GWASs) have succeeded in identifying a number of genomic loci that contribute toward ALS risk and age at onset. However, for the large...

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PMID: 25442119
DOI: 10.1016/j.neurobiolaging.2014.08.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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