Article
A genome-wide association study to identify genetic determinants of atopy in subjects from the United Kingdom.
The Journal of allergy and clinical immunology - 1 Jan 2011
Wan Yize I, Strachan David P, Evans David M, Henderson John, McKeever Tricia, Holloway John W, Hall Ian P, Sayers Ian
Abstract excerpt
BACKGROUND: A genetic component in the development of atopy has been identified. However, numerous heritability models have been proposed with inconsistent replication of susceptibility loci and genes. OBJECTIVE: We sought to use a genome-wide association study approach to examine genetic susceptibility to atopy, which was defined as increased specific IgE levels, positive skin prick test (SPT) responses, or...
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