Article
Beta2-adrenoceptor polymorphisms and asthma from childhood to middle age in the British 1958 birth cohort: a genetic association study.
Lancet (London, England) - 26 Aug 2006
Hall Ian P, Blakey John D, Al Balushi Khalid A, Wheatley Amanda, Sayers Ian, Pembrey Marcus E, Ring Susan M, McArdle Wendy L, Strachan David P
Abstract excerpt
BACKGROUND: Functionally relevant polymorphisms of the beta2-adrenoceptor gene (ADRB2) are common in white populations, but their contribution to the burden of airways disease in the population is uncertain. We aimed to relate the long-term prevalence of asthma or wheeze to functional coding region polymorphisms in the ADRB2 gene. METHODS: The British 1958 birth cohort consisted of all people born in Britain...
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