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Article

Loss of alleles in aprt mutants of CHO cells demonstrated by BclI restriction-fragment-length variation.

Somatic cell and molecular genetics - 1 May 1990

Dewyse P, Bradley W E

Abstract excerpt

A BclI restriction-fragment-length variation (RFLV) has been identified 7 kb downstream of the 3' end of the adenine phosphoribosyltransferase (aprt) gene in the Chinese hamster CHO cell line. This RFLV generates 19 kb and 17 kb + 2 kb BclI fragments. Three other cell lines derived from different Chinese hamsters are homozygous for this RFLV. The 17 kb + 2 kb allele was mapped to the Z4 chromosome based upon the...

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Identifiers

PMID: 1972816
DOI: 10.1007/BF01233358

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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