Studies on the regulatory domain of Ca2+/calmodulin-dependent protein kinase II. Functional analyses of arginine 283 using synthetic inhibitory peptides and site-directed mutagenesis of the alpha subunit.

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Article

Studies on the regulatory domain of Ca2+/calmodulin-dependent protein kinase II. Functional analyses of arginine 283 using synthetic inhibitory peptides and site-directed mutagenesis of the alpha subunit.

The Journal of biological chemistry - 5 Jul 1990

Fong Y L, Soderling T R

Abstract excerpt

The regulatory role of Arg283 in the autoinhibitory domain of Ca2+/calmodulin-dependent protein kinase II was investigated using substituted inhibitory synthetic peptides and site-directed mutation of the expressed kinase. In the synthetic peptide corresponding to the autoinhibitory domain (resid...

Topics

Adenosine Triphosphate
Amino Acid Sequence
Animals
Arginine
Base Sequence
Binding Sites
Binding, Competitive
Calcium
Calcium-Calmodulin-Dependent Protein Kinases
Cattle
DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Egtazic Acid

Glutamates

Glutamic Acid

Glutamine

Immunosorbent Techniques

Kinetics

Lysine

Source

Open in PubMed

Identifiers

PMID: 1972705

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1972705-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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