Modelling genotypes in their microenvironment to predict single- and multi-cellular behaviour

Abstract excerpt

<h4>ABSTRACT</h4> A cell’s phenotype is the set of observable characteristics resulting from the interaction of the genotype with the surrounding environment, determining cell behaviour. Deciphering genotype-phenotype relationships has been crucial to understand normal and disease biology. Analysis of molecular pathways has provided an invaluable tool to such understanding; however, it does typically not consider...

Topics

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• Disease Progression
• Evolution, Molecular
• Genotype
• Models, Genetic
• Models, Theoretical
• Neoplasms
• Neural Networks, Computer
• Phenotype

Identifiers and source

Literature Corpus work

7a0de2f6-d75a-5ab8-8e2d-7a6d37bc0462

DOI

10.1101/360446