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Article

A novel target for treatment of chordoma: signal transducers and activators of transcription 3

1 Sept 2009

Abstract excerpt

A major obstacle in the effective treatment of chordoma is that there are no identifiable biomarkers capable of predicting prognosis. Recent research has indicated that signal transducers and activators of transcription (Stat3) may be an important prognostic marker in some cancers, but its role in chordoma tumors has not been elucidated. In this study, the expression of Stat3 was evaluated in chordoma tissue...

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PMID: 19723879
DOI: 10.1158/1535-7163.mct-09-0504

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