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Article

STAT3: A Potential Drug Target for Tumor and Inflammation

20 Jun 2019

Abstract excerpt

STAT (Signal Transducers and Activators of Transcription) is a cellular signal transcription factor involved in the regulation of many cellular activities, such as cell differentiation, proliferation, angiogenesis in normal cells. During the study of the STAT family, STAT3 was found to be involved in many diseases, such as high expression and sustained activation of STAT3 in tumor cells, promoting tumor growth...

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PMID: 31218960
DOI: 10.2174/1568026619666190620145052

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