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Article

Expression and Therapeutic Potential of SOX9 in Chordoma

12 Jun 2017

Abstract excerpt

Abstract Purpose: Conventional chemotherapeutic agents are ineffective in the treatment of chordoma. We investigated the functional roles and therapeutic relevance of the sex-determining region Y (SRY)-box 9 (SOX9) in chordoma. Experimental Design: SOX9 expression was examined by immunohistochemistry (IHC) using 50 chordoma tissue samples. SOX9 expression in chordoma cell lines was examined by Western blot and...

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Identifiers

PMID: 28606919
DOI: 10.1158/1078-0432.ccr-17-0177

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