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Article

Blockage of Stat3 With CDDO-Me Inhibits Tumor Cell Growth in Chordoma

13 Apr 2010

Abstract excerpt

STUDY DESIGN: An experimental study to investigate the activation of Src/Stat3 pathways in chordomas and blockage of this pathway as a potential strategy for chordoma treatment. OBJECTIVE: To investigate the activation of Src/Stat3 pathway in chordomas cells and to determine the efficiency of inhibiting this pathway by 2-cyano-3,12-dioxooleana-1,9 (11)-dien-28-oic acid-methyl ester (CDDO-Me) as a potential...

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PMID: 20386502
DOI: 10.1097/brs.0b013e3181c2d2b4

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