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Article

HLA-DP variation as additional risk factor in IDDM.

Diabetes - 1 Jul 1990

Easteal S, Kohonen-Corish M R, Zimmet P, Serjeantson S W

Abstract excerpt

A significant increase in the frequency of DPw3/6 alleles defined by restriction-fragment-length polymorphism is observed in insulin-dependent diabetes mellitus (IDDM) patients relative to healthy control subjects (34.6 vs. 10.5%, P less than 0.009). Log-linear modeling demonstrates that this association is independent of HLA-DR3 and -DR4 and IDDM association and cannot be attributed to linkage disequilibrium...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 1972363
DOI: 10.2337/diab.39.7.855

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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HLA-DP variation as additional risk factor in IDDM.PMID 1972363Read ↗

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HLA-encoded genetic predisposition in IDDM: DR4 subtypes may be associated with different degrees of protection.Semantic proximity Read ↗

HLA associations in insulin-dependent diabetes mellitus: no independent association to particular DP genes.Semantic proximity Read ↗

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