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Article

HLA associations in insulin-dependent diabetes mellitus: no independent association to particular DP genes.

Human immunology - 1 Jul 1997

Lie B A, Akselsen H E, Joner G, Dahl-Jørgensen K, Rønningen K S, Thorsby E, Undlien D E

Abstract excerpt

Genes in the HLA complex are associated with susceptibility to develop insulin-dependent diabetes mellitus (IDDM). Several studies, from different populations, have demonstrated strong associations between particular DR and DQ alleles and disease susceptibility or protection. Whether also particu...

Topics

Alleles
Child
Diabetes Mellitus, Type 1
HLA-DP Antigens
HLA-DP alpha-Chains
HLA-DP beta-Chains
HLA-DQ Antigens
Humans

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9361969
DOI: 10.1016/s0198-8859(97)00095-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9361969-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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HLA associations in insulin-dependent diabetes mellitus: no independent association to particular DP genes.PMID 9361969Read ↗

HLA associations in type 1 diabetes: DPB1 alleles may act as markers of other HLA-complex susceptibility genes.Semantic proximity Read ↗

The HLA-DPB1--associated component of the IDDM1 and its relationship to the major loci HLA-DQB1, -DQA1, and -DRB1.Semantic proximity Read ↗

Contribution of DRB1*04 variants to predisposition to or protection from insulin dependent diabetes mellitus is independent of dq.Semantic proximity Read ↗

HLA-encoded genetic predisposition in IDDM: DR4 subtypes may be associated with different degrees of protection.Semantic proximity Read ↗

The HLA class II locus DPB1 can influence susceptibility to type 1 diabetes.Semantic proximity Read ↗

HLA DPA1, DPB1 alleles and haplotypes contribute to the risk associated with type 1 diabetes: analysis of the type 1 diabetes genetics consortium families.Semantic proximity Read ↗

HLA-DP, -DQ and -DR RFLP types in south Indian insulin-dependent diabetes mellitus patients.Semantic proximity Read ↗

HLA-DP polymorphism in Sudanese controls and patients with insulin-dependent diabetes mellitus.Semantic proximity Read ↗

Association of HLA-DPB1 alleles with type I diabetes mellitus in Slovak population.Semantic proximity Read ↗

Implication of specific DQB1 alleles in genetic susceptibility and resistance by identification of IDDM siblings with novel HLA-DQB1 allele and unusual DR2 and DR1 haplotypes.Semantic proximity Read ↗

DRB1*0403 protects against IDDM in Caucasians with the high-risk heterozygous DQA1*0301-DQB1*0302/DQA1*0501-DQB1*0201 genotype. Belgian Diabetes Registry.Semantic proximity Read ↗

HLA-DPB1*0401 is associated with dominant protection against type 1 diabetes in the general Saudi population and in subjects with a high-risk DR/DQ haplotype.Semantic proximity Read ↗

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