Article
Transcriptional repression of the neu protooncogene by the adenovirus 5 E1A gene products.
Proceedings of the National Academy of Sciences of the United States of America - 1 Jun 1990
Yu D, Suen T C, Yan D H, Chang L S, Hung M C
Abstract excerpt
Amplification/overexpression of the human neu protooncogene has been frequently found in human primary breast and ovarian cancers and is correlated with the number of axillary lymph nodes positive for metastasis in breast cancer patients. Identification of the factors controlling transcription of...
Topics
- Adenovirus Early Proteins
- Adenoviruses, Human
- Animals
- Cells, Cultured
- DNA-Binding Proteins
- Gene Expression
- Humans
- Mutation
- Oncogene Proteins, Viral
- Plasmids
- Promoter Regions, Genetic
- Protein-Tyrosine Kinases
- Proto-Oncogene Proteins
- Proto-Oncogenes
- Receptor, ErbB-2
- Repressor Proteins
- Transcription Factors
- Transcription, Genetic