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Article

Transcriptional regulation of neu by RB and E1A in rat-1 cells.

Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Apr 1994

Yu D, Matin A, Hinds P W, Hung M C

Abstract excerpt

Functional inactivation of the tumor-suppressing retinoblastoma gene (Rb) is involved in the etiology of many types of human cancers, including hereditary retinoblastomas. The neu gene is a dominant transforming oncogene, and we previously found that the Rb-encoded protein (RB) suppresses neu-induced transformation in NIH3T3 cells by repressing transcription of the neu oncogene. We report here that RB was unable...

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Identifiers

PMID: 8043517

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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