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Article

Differential gene expression patterns in HER2/neu-positive and -negative breast cancer cell lines and tissues.

The American journal of pathology - 1 Oct 2002

Wilson Katherine S, Roberts Helen, Leek Russell, Harris Adrian L, Geradts Joseph

Abstract excerpt

Overexpression of the oncogene HER2/neu (c-erbB-2) occurs in up to 30% of breast cancers and is correlated with reduced survival, especially in node-positive disease. The aim of this study was to identify genes associated with the aggressive phenotype of HER2/neu-positive breast cancer cells using cDNA microarrays. RNA was extracted from three HER2/neu-positive and three HER2/neu-negative breast cancer cell...

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Source

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Identifiers

PMID: 12368191
DOI: 10.1016/S0002-9440(10)64394-5
PMCID: PMC1867314

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Differential gene expression patterns in HER2/neu-positive and -negative breast cancer cell lines and tissues.PMID 12368191Read ↗

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