Article
Identification of differentially expressed genes associated with HER-2/neu overexpression in human breast cancer cells.
Nucleic acids research - 15 Oct 1999
Oh J J, Grosshans D R, Wong S G, Slamon D J
Abstract excerpt
Amplification and resulting overexpression of the HER-2/ neu proto-oncogene is found in approximately 30% of human breast and 20% of human ovarian cancers. To better understand the molecular events associated with overexpression of this gene in human breast cancer cells, differential hybridization was used to identify genes whose expression levels are altered in cells overexpressing this receptor. Of 16 000...
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