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Article

Deletion mapping on the distal third region of chromosome 1p in multiple endocrine neoplasia type IIA.

Anticancer research - 1 Jan 2000

Yang K P, Nguyen C V, Castillo S G, Samaan N A

Abstract excerpt

Multiple endocrine neoplasia type IIA (MEN IIA) syndrome is an autosomal-dominant endocrine disorder that consists of medullary thyroid carcinoma (MTC), pheochromocytoma, and parathyroid hyperplasia. The susceptibility gene to this disorder has been mapped to chromosome 10. However, molecular studies of tumor cells from patients with familial and sporadic MTC and/or pheochromocytoma have shown a high frequency...

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PMID: 1972009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Deletion mapping on the distal third region of chromosome 1p in multiple endocrine neoplasia type IIA.PMID 1972009Read ↗

Putative parathyroid tumor suppressor on 1p: independent molecular mechanisms of tumorigenesis from 11q allelic loss.Semantic proximity Read ↗

Frequent loss of chromosome arm 1p DNA in parathyroid adenomas.Semantic proximity Read ↗

Genetic events in tumour initiation and progression in multiple endocrine neoplasia type 2.Semantic proximity Read ↗

Localization of the MEN1 gene to a small region within chromosome 11q13 by deletion mapping in tumors.Semantic proximity Read ↗

Sporadic and familial pheochromocytomas are associated with loss of at least two discrete intervals on chromosome 1p.Semantic proximity Read ↗

Genetic mapping of the multiple endocrine neoplasia type 1 locus at 11q13.Semantic proximity Read ↗

Loss of heterozygosity suggests multiple genetic alterations in pheochromocytomas and medullary thyroid carcinomas.Semantic proximity Read ↗

Localisation of a gene causing endocrine neoplasia to a 4 cM region on chromosome 1p35-p36.Semantic proximity Read ↗

Two distinct regions involved in 1p deletion in human primary breast cancer.Semantic proximity Read ↗

Localization of the multiple endocrine neoplasia type I (MEN1) gene based on tumor loss of heterozygosity analysis.Semantic proximity Read ↗

Allelotyping of anaplastic thyroid carcinoma: frequent allelic losses on 1q, 9p, 11, 17, 19p, and 22q.Semantic proximity Read ↗

Genotyping of adrenocortical tumors: very frequent deletions of the MEN1 locus in 11q13 and of a 1-centimorgan region in 2p16.Semantic proximity Read ↗

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