Article
Localisation of a gene causing endocrine neoplasia to a 4 cM region on chromosome 1p35-p36.
Journal of medical genetics - 1 Aug 1997
Williamson C, Pannett A A, Pang J T, Wooding C, McCarthy M, Sheppard M N, Monson J, Clayton R N, Thakker R V
Abstract excerpt
The development of some endocrine tumours, such as medullary thyroid carcinomas, phaeochromocytomas, anterior pituitary adenomas, and parathyroid adenomas involve a putative tumour suppressor gene located on chromosome 1p32-pter, a region that represents 111 cM. In order to refine the location of this gene, 93 endocrine tumours (39 parathyroid adenomas, 40 anterior pituitary adenomas, seven pancreatic islet cell...
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