Article
Genetic events in tumour initiation and progression in multiple endocrine neoplasia type 2.
Genes, chromosomes & cancer - 1 Mar 1993
Mulligan L M, Gardner E, Smith B A, Mathew C G, Ponder B A
Abstract excerpt
Multiple endocrine neoplasia type 2 (MEN 2) is a familial cancer syndrome arising from mutation at a locus or loci in chromosome region 10p11.2-q11.2. The disease is characterized by medullary thyroid carcinoma (MTC) and pheochromocytoma (Pheo). To assess the genetic events in tumour initiation a...
Topics
- Adrenal Gland Neoplasms
- Alleles
- Carcinoma
- Chromosome Mapping
- Chromosomes, Human, Pair 1
- Chromosomes, Human, Pair 10
- Chromosomes, Human, Pair 22
- Chromosomes, Human, Pair 3
- DNA Probes
- Gene Expression Regulation, Neoplastic
- Genes, Tumor Suppressor
- Genetic Markers
- Genotype
- Humans
- Multiple Endocrine Neoplasia
- Pheochromocytoma
- Polymerase Chain Reaction
- Thyroid Neoplasms
