Genetic mapping of the multiple endocrine neoplasia type 1 locus at 11q13.

doi:10.1111/j.1365-2796.1995.tb00931.x

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Article

Genetic mapping of the multiple endocrine neoplasia type 1 locus at 11q13.

Journal of internal medicine - 1 Sept 1995

Teh B T, Cardinal J, Shepherd J, Hayward N K, Weber G, Cameron D, Larsson C

Abstract excerpt

Oncogenesis of tumours related to multiple endocrine neoplasia type 1 (MEN1) is associated with somatic deletions involving the MEN1 locus at chromosomal region 11q13, suggesting inactivation of a tumour-suppressor gene in this region. Here we describe the localization of the MEN1 gene to a 900-k...

Topics

Adult
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 11
Genetic Linkage
Genotype
Heterozygote
Humans
Lod Score
Middle Aged
Multiple Endocrine Neoplasia Type 1
Pedigree
Tasmania

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