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Article

Genetic variation in the vascular endothelial growth factor gene is associated with biliary atresia.

Journal of clinical gastroenterology - 1 Feb 2010

Lee Hung-Chang, Chang Tzu-Yang, Yeung Chun-Yan, Chan Wai-Tao, Jiang Chuen-Bin, Chen Wei-Fang, Chan Hui-Wen, Liu Hsin-Fu, Lin Marie, Lee Yann-Jinn

Abstract excerpt

BACKGROUND AND GOALS: Biliary atresia (BA) is a chronic inflammatory disease of the bile ducts resulting in biliary cirrhosis. Vascular endothelial growth factor (VEGF) has been implicated in cell-mediated inflammatory reactions. We aimed to study the relationship between genetic variations of the VEGF gene and susceptibility to BA using both case-control and family-based methodologies. STUDY: A total of 45...

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PMID: 19713864
DOI: 10.1097/MCG.0b013e3181b152c2

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