Article
+276 G/T single nucleotide polymorphism of the adiponectin gene is associated with the susceptibility to biliary atresia.
World journal of pediatrics : WJP - 1 Nov 2012
Udomsinprasert Wanvisa, Tencomnao Tewin, Honsawek Sittisak, Anomasiri Wilai, Vejchapipat Paisarn, Chongsrisawat Voranush, Poovorawan Yong
Abstract excerpt
BACKGROUND: Biliary atresia (BA) is an intractable neonatal inflammatory and obliterative cholangiopathy, leading to progressive fibrosis and cirrhosis. Adiponectin, an anti-inflammatory adipokine, is known to play a possible role in liver diseases. The objective of our study was to determine the relationship between adiponectin gene polymorphisms and BA susceptibility. METHODS: A total of 106 BA patients and 107...
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