Article
Tumour necrosis factor-alpha gene polymorphisms in Iranian patients with biliary atresia.
African journal of paediatric surgery : AJPS - 1 Jan 2000
Fotouhi Nikou, Bonyadi Morteza, Jahanafrooz Zohreh, Ahmadian Nahid, Sadeghi-Shabestari Mahnaz, Aslanabadi Saeid, Ghergherehchi Robabeh, Pormosavi Milad, Rafeey Mandana
Abstract excerpt
BACKGROUND: Biliary atresia (BA) is a progressive inflammatory destructive process of the bile ducts. This study evaluated the relationship between single-nucleotide polymorphisms in the promoter region of tumour necrosis factor-alpha (TNF-α) gene and bilaiary atresia. MATERIALS AND METHODS: Genomic deoxyribonucleic acid from 16 patients with established diagnosis of BA and 36 patients with INC was obtained. The...
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