Article
Celiac disease is associated with an extended HLA-DR3 haplotype which includes HLA-DPw1.
Human immunology - 1 Mar 1990
Hall M A, Lanchbury J S, Bolsover W J, Welsh K I, Ciclitira P J
Abstract excerpt
HLA-DP polymorphism was examined among celiac disease patients and controls. Restriction fragment length polymorphism (RFLP) genotyping showed a significant association of DPw1 in celiac disease (32/80) compared with controls (6/53, p = 0.0002). DPw1 typing by RFLP was verified using DPB1-amplified DNA and an oligonucleotide probe specific for the DPw1-associated DPB1 gene. The RFLP-assigned DPw1 genotype...
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