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Article

Celiac disease is associated with an extended HLA-DR3 haplotype which includes HLA-DPw1.

Human immunology - 1 Mar 1990

Hall M A, Lanchbury J S, Bolsover W J, Welsh K I, Ciclitira P J

Abstract excerpt

HLA-DP polymorphism was examined among celiac disease patients and controls. Restriction fragment length polymorphism (RFLP) genotyping showed a significant association of DPw1 in celiac disease (32/80) compared with controls (6/53, p = 0.0002). DPw1 typing by RFLP was verified using DPB1-amplifi...

Topics

Base Sequence
Blotting, Southern
Celiac Disease
Chi-Square Distribution
Cloning, Molecular
Genotype
HLA-DP Antigens
HLA-DP beta-Chains
HLA-DR3 Antigen
Haplotypes
Histocompatibility Testing
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Oligonucleotide Probes

Polymerase Chain Reaction

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 1971269
DOI: 10.1016/0198-8859(90)90052-q

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1971269-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Celiac disease is associated with an extended HLA-DR3 haplotype which includes HLA-DPw1.PMID 1971269Read ↗

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