A family study confirms that the HLA-DP associations with celiac disease are the result of an extended HLA-DR3 haplotype.

doi:10.1016/0198-8859(91)90012-x

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Article

A family study confirms that the HLA-DP associations with celiac disease are the result of an extended HLA-DR3 haplotype.

Human immunology - 1 Jun 1991

Bolsover W J, Hall M A, Vaughan R W, Welsh K I, Ciclitira P J

Abstract excerpt

Genotyping for HLA-DR, -DQ, and -DP antigens by restriction fragment length polymorphism (RFLP) analysis along with identification of restriction fragments associated with celiac disease (CD) were undertaken in 13 families in which more than one member had CD. Major histocompatibility complex class II haplotypes for the family members were constructed which included both genotypes and RFLP markers. In 12 of the...

Topics

Adolescent
Adult
Celiac Disease
Child
DNA Restriction Enzymes
Family
Female
Genotype
HLA-DP Antigens
HLA-DR3 Antigen
Haplotypes
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Infant

Male

Middle Aged

Pedigree

Polymorphism, Restriction Fragment Length

Restriction Mapping

Source

Open in PubMed

Identifiers

PMID: 1676703
DOI: 10.1016/0198-8859(91)90012-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1676703-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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A family study confirms that the HLA-DP associations with celiac disease are the result of an extended HLA-DR3 haplotype.PMID 1676703Read ↗

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