HLA-DR, DQ genotypes of celiac disease patients and healthy subjects from the West of Ireland.

doi:10.1111/j.1399-0039.1996.tb02525.x

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Article

HLA-DR, DQ genotypes of celiac disease patients and healthy subjects from the West of Ireland.

Tissue antigens - 1 Feb 1996

Michalski J P, McCombs C C, Arai T, Elston R C, Cao T, McCarthy C F, Stevens F M

Abstract excerpt

Celiac disease (CD) has one of the strongest class II HLA associations of any human illness. We used DNA-RFLP typing to study the class II HLA genotypes of celiac disease patients from the West of Ireland, the geographic area with the highest rate of celiac disease in the world. We confirmed the high frequency of HLA-DR3 in this population, and we were also able to demonstrate the additional risk of developing...

Topics

Celiac Disease
Follow-Up Studies
Genotype
HLA-DQ Antigens
HLA-DR Antigens
HLA-DR3 Antigen
HLA-DR4 Antigen
HLA-DR7 Antigen
Haplotypes
Histocompatibility Antigens Class II
Humans
Ireland

Source

Open in PubMed

Identifiers

PMID: 8851726
DOI: 10.1111/j.1399-0039.1996.tb02525.x

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