Article
HLA-DP polymorphism in northern Italian celiac patients.
Tissue antigens - 1 Oct 1992
Mantovani V, Corazza G R, Frisoni M, Zaniboni M G, Bragliani M, Valentini R A, Barboni P, Lambertini A, Gasbarrini G
Abstract excerpt
The contribution of HLA-DP genes to celiac disease susceptibility has been investigated in 95 Italian patients, 41 with childhood and 54 with adult disease onset. Polymerase chain reaction amplification, sequence-specific oligonucleotide probe hybridization and restriction fragment length polymorphism analyses have been carried out. All celiac patients and 56 out of 128 random healthy controls were DQw2-positive....
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