Extended major histocompatibility complex haplotypes in celiac patients in the west of Ireland.

doi:10.1002/ajmg.1320450319

Back to search

Article

Extended major histocompatibility complex haplotypes in celiac patients in the west of Ireland.

American journal of medical genetics - 1 Feb 1993

Mannion A, Stevens F M, McCarthy C F, Grimes-O'Cearbhaill H, Killeen A A

Abstract excerpt

The highest reported prevalence of celiac disease (gluten-sensitive enteropathy) is found in the West of Ireland. Recent genetic data have suggested that major histocompatibility complex-linked loci may have a dominant genetic effect for disease susceptibility in this population compared with a r...

Topics

Adult
Alleles
Celiac Disease
Child
Complement C4
Complement System Proteins
Female
Genetic Markers
HLA-B8 Antigen
Haplotypes
Humans
Ireland
Major Histocompatibility Complex
Male

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.