Article
Extended major histocompatibility complex haplotypes in celiac patients in the west of Ireland.
American journal of medical genetics - 1 Feb 1993
Mannion A, Stevens F M, McCarthy C F, Grimes-O'Cearbhaill H, Killeen A A
Abstract excerpt
The highest reported prevalence of celiac disease (gluten-sensitive enteropathy) is found in the West of Ireland. Recent genetic data have suggested that major histocompatibility complex-linked loci may have a dominant genetic effect for disease susceptibility in this population compared with a recessive effect in other groups. To further understand the role of the MHC in celiac disease in the West of Ireland, we...
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