HLA class II alleles associated with celiac disease susceptibility in a southern European population.

doi:10.1111/j.1399-0039.1992.tb01965.x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

HLA class II alleles associated with celiac disease susceptibility in a southern European population.

Tissue antigens - 1 Aug 1992

Tighe M R, Hall M A, Barbado M, Cardi E, Welsh K I, Ciclitira P J

Abstract excerpt

Susceptibility to celiac disease in Northern Europe is associated with the human leukocyte antigens (HLA) B8, DR3 and DQ2, which exist together on an extended haplotype. The strong predominance of this haplotype within the Northern European celiac populations, together with the linkage disequilibrium which occurs between these loci, does not allow identification of the gene(s) primarily associated with disease...

Topics

Adolescent
Adult
Alleles
Base Sequence
Blotting, Southern
Celiac Disease
Child
Child, Preschool
DNA
Disease Susceptibility
Europe
Gene Amplification

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HLA-DQ Antigens

HLA-DR3 Antigen

HLA-DR7 Antigen

Haplotypes

Histocompatibility Antigens Class II

Humans

Source

Open in PubMed

Identifiers

PMID: 1357780
DOI: 10.1111/j.1399-0039.1992.tb01965.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1357780-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA class II alleles associated with celiac disease susceptibility in a southern European population.PMID 1357780Read ↗

HLA-DP polymorphism in northern Italian celiac patients.Semantic proximity Read ↗

Molecular characterization of HLA class II genes in celiac disease patients of Latin American Caucasian origin.Semantic proximity Read ↗

Genetic susceptibilty and celiac disease: what role do HLA haplotypes play?Semantic proximity Read ↗

HLA Genotyping: Methods for the Identification of the HLA-DQ2,-DQ8 Heterodimers Implicated in Celiac Disease (CD) Susceptibility.Semantic proximity Read ↗

High Frequency of Haplotype HLA-DQ7 in Celiac Disease Patients from South Italy: Retrospective Evaluation of 5,535 Subjects at Risk of Celiac Disease.Semantic proximity Read ↗

T-cell receptor variable genes and genetic susceptibility to celiac disease: an association and linkage study.Semantic proximity Read ↗

HLA class II high-resolution genotyping in Greek children with celiac disease and impact on disease susceptibility.Semantic proximity Read ↗

Role of HLA-DQB1 alleles in the risk, signs and symptoms, and severity of celiac disease in a Venezuelan population.Semantic proximity Read ↗

Allele and haplotype frequencies for HLA class II (DQA1 and DQB1) loci in patients with celiac disease from Spain.Semantic proximity Read ↗

Celiac disease among Ashkenazi Jews from Israel. A study of the HLA class II alleles and their associations with disease susceptibility.Semantic proximity Read ↗

Genetic predisposition to celiac disease in Kazakhstan: Potential impact on the clinical practice in Central Asia.Semantic proximity Read ↗

HLA class II frequencies in celiac disease patients in the west of Ireland.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.