Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single nucleotide polymorphism on chromosome 9p21 and endothelial progenitor cells in a general population cohort.

Atherosclerosis - 1 Feb 2010

Ye Shu, Willeit Johann, Xiao Qingzhong, Motterle Anna, Laxton Ross C, Oberhollenzer Friedrich, Kiechl Stefan, Xu Qingbo

Abstract excerpt

OBJECTIVE: Recent studies have revealed that sequence variation on chromosome 9p21 is a major genetic determinant for coronary heart disease and stroke, however, the underlying mechanism remains unknown. This genomic region contains the gene encoding cyclin-dependent kinase 2A, a regulator of proliferation and differentiation of endothelial progenitor cell (EPC) which has been implicated in vascular repair and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiovascular Diseases
Share to Cell Proliferation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 9

Share to Cohort Studies

Share to Cyclin-Dependent Kinase Inhibitor p16

Share to Endothelial Cells

Share to Stem Cells

Source

Identifiers

PMID: 19709660
DOI: 10.1016/j.atherosclerosis.2009.08.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single nucleotide polymorphism on chromosome 9p21 and endothelial progenitor cells in a general population cohort.PMID 19709660Read ↗

Chromosome 9p21 and Cardiovascular DiseaseSemantic proximity Read ↗

Candidate gene polymorphisms and the 9p21 locus in acute coronary syndromes.Semantic proximity Read ↗

Association of genetic variation on chromosome 9p21 with susceptibility and progression of atherosclerosis: a population-based, prospective study.Semantic proximity Read ↗

Evidence for genetic regulation of endothelial progenitor cells and their role as biological markers of atherosclerotic susceptibility.Semantic proximity Read ↗

Preeclampsia does not share common risk alleles in 9p21 with coronary artery disease and type 2 diabetes.Semantic proximity Read ↗

Microarray-based characterization of a colony assay used to investigate endothelial progenitor cells and relevance to endothelial function in humans.Semantic proximity Read ↗

Genetic and clinical correlates of early-outgrowth colony-forming units.Semantic proximity Read ↗

Chromosome 9p21 genetic variation explains 13% of cardiovascular disease incidence but does not improve risk prediction.Semantic proximity Read ↗

Coronary artery disease-associated locus on chromosome 9p21 and early markers of atherosclerosis.Semantic proximity Read ↗

SDF1 gene variation is associated with circulating SDF1alpha level and endothelial progenitor cell number: the Bruneck Study.Semantic proximity Read ↗

Functional analyses of coronary artery disease associated variation on chromosome 9p21 in vascular smooth muscle cells.Semantic proximity Read ↗

The 9p21 locus does not affect risk of coronary artery disease through induction of type 1 interferons.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.