Article
Evidence for genetic regulation of endothelial progenitor cells and their role as biological markers of atherosclerotic susceptibility.
European heart journal - 1 Feb 2008
Whittaker Andrew, Moore Jasbir S, Vasa-Nicotera Mariuca, Stevens Suzanne, Samani Nilesh J
Abstract excerpt
AIMS: Endothelial progenitor cells (EPCs) are found in the peripheral circulation and are capable of endothelial repair and neovascularization. EPC number and function are reduced in subjects with cardiovascular risk factors or proven coronary artery disease (CAD). We hypothesized that EPC number and/or function may be genetically regulated and may vary in healthy adult offspring depending on parental history of...
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