Article
Genetic and clinical correlates of early-outgrowth colony-forming units.
Circulation. Cardiovascular genetics - 1 Jun 2011
Shaw Stanley Y, Cheng Susan, Cupples L Adrienne, Larson Martin G, McCabe Elizabeth L, Ngwa Julius S, Wang Ying A, Martin Roderick P, Klein Rachael J, Hashmi Basma, Ajijola Olujimi A, Lau Evan, O'Donnell Christopher J, Vasan Ramachandran S, Cohen Kenneth S, Wang Thomas J
Abstract excerpt
BACKGROUND: Several bone marrow-derived cell populations may have angiogenic activity, including cells termed endothelial progenitor cells. Decreased numbers of circulating angiogenic cell populations have been associated with increased cardiovascular risk. However, few data exist from large, unselected samples, and the genetic determinants of these traits are unclear. METHODS AND RESULTS: We examined the...
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