Article
SDF1 gene variation is associated with circulating SDF1alpha level and endothelial progenitor cell number: the Bruneck Study.
PloS one - 1 Jan 2008
Xiao Qingzhong, Ye Shu, Oberhollenzer Friedrich, Mayr Agnes, Jahangiri Marjan, Willeit Johann, Kiechl Stefan, Xu Qingbo
Abstract excerpt
BACKGROUND: Stromal cell-derived factor-1 (SDF1) and its receptor CXC chemokine receptor 4 (CXCR4) play a critical role in progenitor cell homing, mobilization and differentiation. It would be interesting to assess the predictive value of SDF-1alpha level for EPC number, and to ascertain whether there is a relationship between SDF1 gene variation, plasma SDF-1alpha level, and the number and function of...
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