Article
Preeclampsia does not share common risk alleles in 9p21 with coronary artery disease and type 2 diabetes.
Annals of medicine - 1 Aug 2016
Kaartokallio Tea, Lokki A Inkeri, Peterson Hanna, Kivinen Katja, Hiltunen Leena, Salmela Elina, Lappalainen Tuuli, Maanselkä Paula, Heino Sanna, Knuutila Sakari, Sayed Ayat, Poston Lucilla, Brennecke Shaun P, Johnson Matthew P, Morgan Linda, Moses Eric K, Kere Juha, Laivuori Hannele
Abstract excerpt
INTRODUCTION: Preeclampsia is a common and partially genetic pregnancy complication characterized by hypertension and proteinuria. Association with cardiovascular disease and type 2 diabetes has been reported in 9p21 by several genome-wide association studies. It has been hypothesized that cardiometabolic diseases may share common etiology with preeclampsia. MATERIALS AND METHODS: We tested association with the...
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