Article
Extracellular matrix from normal but not Steel mutant mice enhances melanogenesis in cultured mouse neural crest cells.
Developmental biology - 1 Jun 1990
Morrison-Graham K, West-Johnsrud L, Weston J A
Abstract excerpt
The Steel mutation is a non-cell-autonomous defect in mice that affects the development of several stem cell populations, including germ cells, hematopoietic cells, and neural crest-derived pigment cells. To characterize the environmental lesion caused by the Steel mutation, we have compared the ability of normal and mutant extracellular matrix material to support the differentiation of normal mouse neural crest...
Topics
- Animals
- Cell Differentiation
- Cells, Cultured
- Extracellular Matrix
- Melanocytes
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Microscopy, Electron, Scanning
- Mutation
- Neural Crest