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Article

Derivation of melanocytes from embryonic stem cells in culture.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Dec 1999

Yamane T, Hayashi S, Mizoguchi M, Yamazaki H, Kunisada T

Abstract excerpt

We report that embryonic stem (ES) cells were efficiently induced to differentiate to melanocytes in vitro. When undifferentiated ES cells were cocultured with a bone marrow-derived stromal cell line, a very small but significant number of melanocytes were reproducibly generated. This process was greatly enhanced by addition of dexamethasone to the culture and strictly depended on steel factor, the ligand for the...

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Identifiers

PMID: 10633864
DOI: 10.1002/(SICI)1097-0177(199912)216:4/5<450::AID-DVDY13>3.0.CO;2-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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