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Article

GCF2/LRRFIP1 represses tumor necrosis factor alpha expression.

Molecular and cellular biology - 1 Oct 2005

Suriano April R, Sanford Amy N, Kim Nahmah, Oh Miae, Kennedy Sarah, Henderson Mark J, Dietzmann Kelly, Sullivan Kathleen E

Abstract excerpt

Tumor necrosis factor alpha (TNF-alpha) is an important mediator of inflammation, apoptosis, and the development of secondary lymphoid structures. Multiple polymorphic microsatellites have been identified in and around the gene, and there are also multiple single-base pair biallelic polymorphisms in the introns and promoter. The TNF-alpha -308 promoter polymorphism is a G-to-A transition which has been...

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Source

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Identifiers

PMID: 16199883
DOI: 10.1128/MCB.25.20.9073-9081.2005
PMCID: PMC1265793

Genes

TNF
LRRFIP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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