A novel method to express SNP-based genetic heterogeneity, Psi, and its use to measure linkage disequilibrium for multiple SNPs, D(g), and to estimate absolute maximum of haplotype frequency.

Abstract excerpt

Single nucleotide polymorphisms (SNPs) are important markers to investigate genetic heterogeneity of population and to perform linkage disequilibrium (LD) mapping. We propose a new method, Psi, to express frequency of 2(N(s)) haplotypes for N(s) di-allelic SNPs. Using the new expression of haplot...

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