Article
Vitamin D related genes, CYP24A1 and CYP27B1, and colon cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 2009
Dong Linda M, Ulrich Cornelia M, Hsu Li, Duggan David J, Benitez Debbie S, White Emily, Slattery Martha L, Farin Fred M, Makar Karen W, Carlson Christopher S, Caan Bette J, Potter John D, Peters Ulrike
Abstract excerpt
Genetic association studies investigating the role of vitamin D in colon cancer have primarily focused on the vitamin D receptor (VDR), with limited data available for other genes in the vitamin D pathway, including vitamin D activating enzyme 1-alpha hydroxylase (CYP27B1) and vitamin D deactivating enzyme 24-alpha hydroxylase (CYP24A1). We evaluated whether 12 tagging single nucleotide polymorphisms (SNP) in...
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