Article
Genetic variation in vitamin D-related genes and risk of colorectal cancer in African Americans.
Cancer causes & control : CCC - 1 May 2014
Pibiri Fabio, Kittles Rick A, Sandler Robert S, Keku Temitope O, Kupfer Sonia S, Xicola Rosa M, Llor Xavier, Ellis Nathan A
Abstract excerpt
PURPOSE: Disparities in both colorectal cancer (CRC) incidence and survival impact African Americans (AAs) more than other US ethnic groups. Because vitamin D is thought to protect against CRC and AAs have lower serum vitamin D levels, genetic variants that modulate the levels of active hormone in the tissues could explain some of the cancer health disparity. Consequently, we hypothesized that genetic variants in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
